An international collaboration has found for the first time that two new epigenetic regulators, TAF5L and TAF6L, maintain self-renewal of embryonic stem cells. The scientists also found that these proteins activate c-Myc (a well-known cancer gene), and its regulatory network. This is the first time scientists have been able to show what these regulators do and how they control gene expression.
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers have taken an important first step: They used near-infrared light and an injected DNA nanodevice to guide stem cells to an injury, which helped muscle tissue regrow in mice.